Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | MET | P08581 | 3/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 1/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | MST1R | Q04912 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26881431 | 1.00 | AURKA (0.35) | AURKATTKAURKBINCENPACLY | |
| SCHEMBL27009554 | 1.00 | AURKA (0.35) | AURKATTKAURKBINCENPACLY | |
| SCHEMBL27132366 | 0.93 | PIK3CA (0.33) | PIK3CACDK2AKT1AKT2AKT3 | |
| SCHEMBL27008395 | 0.93 | PIK3CA (0.33) | PIK3CACDK2AKT1AKT2AKT3 | |
| SCHEMBL30742146 | 0.93 | PIK3CA (0.33) | PIK3CACDK2AKT1AKT2AKT3 | |
| SCHEMBL30928408 | 0.89 | ACLY (0.37) | AURKATTKAURKBINCENPACLY | |
| SCHEMBL30928402 | 0.89 | ACLY (0.37) | AURKATTKAURKBINCENPACLY | |
| SCHEMBL27129172 | 0.88 | PRMT5 (0.37) | PIK3CACDK2AKT1AKT2AKT3 | |
| SCHEMBL26881834 | 0.88 | PRMT5 (0.37) | PIK3CACDK2AKT1AKT2AKT3 | |
| SCHEMBL27129795 | 0.87 | PIK3CA (0.39) | AURKATTKAURKBINCENPPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874676-A | PI3K inhibitor and preparation method and application thereof | 海创药业股份有限公司 | 2025-04-25 | — | — | CN | disclosed |