SCHEMBL3148208

SCHEMBL3148208

COc1cc(C(=O)NCC2CCCCC2)cc(OC)c1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 1.00
KMT2A Q03164 3/20 0.64
ABCG2 Q9UNQ0 1/20 0.61
POLB P06746 2/20 0.59
ALDH1A1 P00352 1/20 0.58
MEN1 O00255 2/20 0.57
TP53 P04637 1/20 0.56
SIRT5 Q9NXA8 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MMP13 P45452 1/20 0.52
SLC29A1 Q99808 1/20 0.52
ATM Q13315 1/20 0.52
MAPK1 P28482 1/20 0.51
OPRK1 P41145 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4248420 0.85 TDP1 (0.74) TDP1KMT2AABCG2POLBALDH1A1
SCHEMBL8595899 0.85 TDP1 (0.74) TDP1KMT2AABCG2POLBMEN1
Hydrochloric Acid SCHEMBL11714021 0.85 TDP1 (0.74) TDP1KMT2AABCG2POLBMEN1
SCHEMBL3132900 0.85 TDP1 (0.74) TDP1KMT2APOLBALDH1A1MEN1
SCHEMBL3138997 0.85 TDP1 (0.74) TDP1KMT2APOLBMEN1MMP13
SCHEMBL12799554 0.84 TDP1 (0.72) TDP1KMT2AABCG2POLBALDH1A1
SCHEMBL3230786 0.82 TDP1 (0.68) TDP1KMT2AABCG2POLBALDH1A1
SCHEMBL2917118 0.82 TDP1 (0.68) TDP1KMT2APOLBMEN1SMN1; SMN2
SCHEMBL13175544 0.82 TDP1 (0.69) TDP1KMT2APOLBALDH1A1MEN1
SCHEMBL6643674 0.82 TDP1 (0.69) TDP1KMT2AABCG2POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-06-03 US disclosed
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-06-03 US disclosed
EP-2179651-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2010-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD CBR3, CBR1, HDHD5 TDP1 4583/4885KMT2A 1467/4885ABCG2 4770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.