SCHEMBL31482811

SCHEMBL31482811

CCSc1ccc(C(=O)Nc2ccc3c(c2)c(N2CCC(F)(F)CC2)nn3C)c(N2CCC3(CC2)CC3)c1

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31482877 0.88 KIF18A (0.44) KIF18A
SCHEMBL31482828 0.88 KIF18A (0.45) KIF18A
SCHEMBL31482819 0.88 KIF18A (0.43) KIF18A
SCHEMBL30896802 0.87 KIF18A (0.47) KIF18A
SCHEMBL31482856 0.86 KIF18A (0.48) KIF18A
SCHEMBL30896813 0.86 KIF18A (0.46) KIF18A
SCHEMBL31482857 0.86 KIF18A (0.41) KIF18A
SCHEMBL31482869 0.86 KIF18A (0.41) KIF18A
SCHEMBL31482868 0.85 KIF18A (0.47) KIF18A
SCHEMBL31482821 0.84 KIF18A (0.46) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894878-A Aromatic amide derivative and preparation method and application thereof 浙江海正药业股份有限公司 2025-04-25 — — CN disclosed
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