SCHEMBL3148290

SCHEMBL3148290

CN1c2ccc(Br)cc2C(C)(C)C12C=Nc1c(ccc3cnccc13)O2

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
KDM4E B2RXH2 4/20 0.58
THRB P10828 4/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
ALOX12 P18054 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
PKM P14618 1/20 0.58
LMNA P02545 3/20 0.52
GAA P10253 3/20 0.52
ALDH1A1 P00352 2/20 0.52
HPGD P15428 2/20 0.52
HTT P42858 2/20 0.52
RECQL P46063 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
POLB P06746 1/20 0.52
MAPK1 P28482 1/20 0.52
NPSR1 Q6W5P4 3/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4980717 0.89 MAPT (0.59) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3161042 0.88 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL4002922 0.88 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3162588 0.88 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL14870331 0.87 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3158374 0.87 MAPT (0.67) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3164187 0.86 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29715802 0.86 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3164466 0.86 MAPT (0.55) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3154813 0.86 MAPT (0.55) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754614-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2009-06-17 EP claimed
CN-114729218-A Ink composition for inkjet recording and image recording method 富士胶片株式会社 2022-07-08 CN disclosed
EP-2690495-A1 Lithographic printing plate precursor and plate making method thereof Fujifilm Corporation (JP) 2014-01-29 EP disclosed
EP-1498447-B1 Photochromic material PILOT INK CO LTD (JP) 2010-02-24 EP disclosed
EP-1754614-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2009-06-17 EP disclosed
US-7524605-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2009-04-28 US disclosed
US-7351362-B2 Photochromic material THE PILOT INK CO., LTD. (JP) 2008-04-01 US disclosed
EP-1584485-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2007-12-05 EP disclosed
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed
EP-1754614-A1 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2007-02-21 EP disclosed
US-20050271976-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2005-12-08 US disclosed
EP-1584485-A2 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2005-10-12 EP disclosed
EP-1498447-A1 Photochromic material THE PILOT INK CO., LTD. (JP) 2005-01-19 EP disclosed