SCHEMBL14870331

SCHEMBL14870331

CN1c2ccc(Br)cc2C(C)(C)C12C=Nc1c(ccc3ccccc13)O2

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.77
KDM4E B2RXH2 5/20 0.77
THRB P10828 4/20 0.77
SMN1; SMN2 Q16637 4/20 0.77
ALOX12 P18054 2/20 0.77
L3MBTL1 Q9Y468 2/20 0.77
PKM P14618 1/20 0.77
HTT P42858 3/20 0.62
LMNA P02545 3/20 0.62
GAA P10253 3/20 0.62
ALDH1A1 P00352 2/20 0.62
HPGD P15428 2/20 0.62
RECQL P46063 2/20 0.62
TDP1 Q9NUW8 2/20 0.62
MAPK1 P28482 2/20 0.62
POLB P06746 1/20 0.62
NPSR1 Q6W5P4 4/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2183705 0.93 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL4620865 0.88 MAPT (0.78) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3439007 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493005 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL1626757 0.88 MAPT (0.77) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL3148290 0.87 MAPT (0.58) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL80364 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL13839771 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL29493002 0.87 MAPT (1.00) MAPTKDM4ETHRBSMN1; SMN2ALOX12
SCHEMBL9996010 0.86 MAPT (0.80) MAPTKDM4ETHRBSMN1; SMN2ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023220461-A1 PHOTOINITIATORS, COMPOSITIONS, AND METHODS OF FORMING AN OBJECT QUADRATIC 3D, INC. (US) 2023-11-16 WO disclosed
US-9063358-B2 Smart photochromic chiral nematic liquid crystal window KENT STATE UNIVERSITY (US) 2015-06-23 US disclosed
US-9063358-B2 Smart photochromic chiral nematic liquid crystal window KENT STATE UNIVERSITY (US) 2015-06-23 US disclosed
US-20130093969-A1 SMART PHOTOCHROMIC CHIRAL NEMATIC LIQUID CRYSTAL WINDOW KENT STATE UNIVERSITY (US) 2013-04-18 US disclosed
US-20130093969-A1 SMART PHOTOCHROMIC CHIRAL NEMATIC LIQUID CRYSTAL WINDOW KENT STATE UNIVERSITY (US) 2013-04-18 US disclosed