Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11818061 | 0.85 | EPHX2 (0.51) | G6PDEPHX2LMNABLMHPGD | |
| SCHEMBL13232125 | 0.82 | G6PD (0.38) | G6PDEPHX2LMNABLMHPGD | |
| SCHEMBL17251654 | 0.81 | ATM (0.44) | EPHX2LMNABLMHPGDSHPGD | |
| SCHEMBL1034667 | 0.81 | GRIN1 (0.42) | EPHX2LMNABLMHPGDSHPGD | |
| SCHEMBL1723506 | 0.81 | GRIN1 (0.42) | EPHX2LMNABLMHPGDSHPGD | |
| SCHEMBL2194478 | 0.81 | GRIN1 (0.42) | EPHX2LMNABLMHPGDSHPGD | |
| SCHEMBL15233305 | 0.80 | EPHX2 (0.37) | G6PDEPHX2LMNABLMMAPT | |
| SCHEMBL22311168 | 0.78 | G6PD (0.43) | G6PDEPHX2LMNABLMHPGDS | |
| SCHEMBL21913642 | 0.78 | EPHX2 (0.45) | G6PDEPHX2LMNABLMHPGDS | |
| SCHEMBL6495439 | 0.78 | G6PD (0.43) | G6PDEPHX2LMNABLMHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |