Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CAD | P27708 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483112 | 1.00 | PAX8 (0.38) | PAX8CNR1TGFBR1NPC1ALDH1A1 | |
| SCHEMBL4330718 | 0.80 | CNR1 (0.36) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL16648831 | 0.78 | CNR1 (0.39) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL11069078 | 0.78 | MAPT (0.42) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL16348942 | 0.78 | MAPT (0.42) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL4341764 | 0.78 | MEN1 (0.38) | PAX8CNR1CA1CA2CA7 | |
| SCHEMBL1120240 | 0.78 | CNR1 (0.39) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL14350678 | 0.78 | MAPT (0.42) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL1261511 | 0.78 | CNR1 (0.39) | PAX8CNR1TGFBR1ALDH1A1CA1 | |
| SCHEMBL25159573 | 0.77 | PAX8 (0.36) | PAX8CNR1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |