Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | PDE8B | O95263 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SPNS2 | Q8IVW8 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1751510 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL29020219 | 0.86 | TDP1 (0.41) | CYP2A6PDE8BKCNH2ALDH1A1PDE10A | |
| SCHEMBL12425628 | 0.82 | HSD11B1 (0.39) | PDE8BKCNH2ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL20045386 | 0.80 | TDP1 (0.43) | KCNH2ALDH1A1SPNS2SMN1; SMN2L3MBTL1 | |
| SCHEMBL3327111 | 0.80 | JAK2 (0.40) | PDE8BKCNH2ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL3321189 | 0.80 | KCNH2 (0.37) | PDE8BKCNH2ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL243921 | 0.79 | — | — | |
| SCHEMBL23709740 | 0.78 | TDP1 (0.42) | ALDH1A1SPNS2SMN1; SMN2L3MBTL1 | |
| SCHEMBL19441245 | 0.78 | TDP1 (0.42) | ALDH1A1SPNS2SMN1; SMN2L3MBTL1 | |
| SCHEMBL9776 | 0.78 | MEN1 (0.43) | ALDH1A1SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119841829-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2025-04-18 | — | — | CN | disclosed |