Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27110752 | 1.00 | ESR1 (0.50) | ESR1CA12CA1CA9SREBF2 | |
| SCHEMBL27110779 | 0.85 | ESR1 (0.51) | ESR1CA12CA1CA9SREBF2 | |
| SCHEMBL30846872 | 0.85 | ESR1 (0.51) | ESR1CA12CA1CA9SREBF2 | |
| SCHEMBL27153339 | 0.84 | ALDH1A1 (0.41) | ESR1MAP4K4NPC1RAB9ATDP1 | |
| SCHEMBL31483499 | 0.78 | ALDH1A1 (0.52) | PSMB8BCL2NPC1RAB9ATDP1 | |
| SCHEMBL29130752 | 0.77 | AKR1C3 (0.43) | PSMB8BCL2TDP1BECN1CYP17A1 | |
| SCHEMBL29130759 | 0.76 | MEN1 (0.47) | BCL2TDP1BECN1CYP17A1 | |
| SCHEMBL27110732 | 0.74 | NPC1 (0.39) | CA12CA1CA9BCL2NPC1 | |
| SCHEMBL467281 | 0.74 | KMT2A (0.56) | PSMB8BCL2NPC1RAB9ABECN1 | |
| SCHEMBL29131710 | 0.74 | HPGD (0.59) | CA12CA1CA9PSMB8MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119768396-A | Novel substituted benzothiophene-6-carboxylic acid derivatives, process for their preparation and their therapeutic use | 赛诺菲 | 2025-04-04 | — | — | CN | disclosed |