Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23126448 | 0.85 | ENPP2 (0.37) | ENPP2ORAI1ORAI2ORAI3SLC6A4 | |
| SCHEMBL29956826 | 0.82 | ENPP2 (0.55) | ENPP2MCHR1ORAI1ORAI2ORAI3 | |
| SCHEMBL2405931 | 0.82 | ENPP2 (0.55) | ENPP2MCHR1ORAI1ORAI2ORAI3 | |
| SCHEMBL28414854 | 0.81 | ENPP2 (0.41) | ENPP2MCHR1ORAI1ORAI2ORAI3 | |
| SCHEMBL1124755 | 0.76 | ENPP2 (0.63) | ENPP2HPGDORAI1ORAI2ORAI3 | |
| SCHEMBL29427143 | 0.76 | ENPP2 (0.63) | ENPP2HPGDORAI1ORAI2ORAI3 | |
| SCHEMBL21979744 | 0.75 | ENPP2 (0.52) | ENPP2MCHR1ORAI1ORAI2ORAI3 | |
| SCHEMBL29951150 | 0.75 | ENPP2 (0.46) | ENPP2HPGDORAI1ORAI2ORAI3 | |
| SCHEMBL14120757 | 0.75 | ENPP2 (0.46) | ENPP2HPGDORAI1ORAI2ORAI3 | |
| SCHEMBL29955587 | 0.75 | ENPP2 (0.52) | ENPP2MCHR1ORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111148744-B | Novel heterocyclic compounds as MGLUR7 modulators | 布拉格玛治疗公司 | 2025-02-14 | — | — | CN | disclosed |