Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118620 | 1.00 | KDM4E (0.72) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10262840 | 0.87 | KDM4E (0.62) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2039522 | 0.85 | KDM4E (0.60) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2118708 | 0.83 | ALDH1A1 (0.58) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6093891 | 0.83 | SMN1; SMN2 (0.57) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL402452 | 0.82 | PDE5A (0.57) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2118255 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL37938 | 0.81 | PDE5A (0.77) | KDM4ERECQLALDH1A1SMN1; SMN2HTT | |
| SCHEMBL24329791 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL2117452 | 0.80 | KDM4E (0.54) | KDM4ERECQLALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699176-B | Quinazolinones as PARP14 inhibitors | 里邦医疗公司 | 2025-02-14 | — | — | CN | disclosed |