SCHEMBL31484409

SCHEMBL31484409

O=c1[nH]cc([N+](=O)[O-])c2sccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 3/20 0.41
RAB9A P51151 1/20 0.39
PARP1 P09874 6/20 0.36
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
MAPT P10636 2/20 0.34
TSHR P16473 2/20 0.34
BLM P54132 2/20 0.34
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
GRIK1 P39086 1/20 0.34
GRIA1 P42261 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
GRIA4 P48058 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836959 0.73 HTR2A (0.36) ALDH1A1KDM4ERAB9APARP1CYP1A2
SCHEMBL9837755 0.73 HTR2A (0.36) ALDH1A1KDM4ERAB9APARP1CYP1A2
SCHEMBL5240090 0.72 GSK3B (0.45) ALDH1A1KDM4EPARP1ADORA2AADORA1
SCHEMBL15717048 0.72 ALDH1A1 (0.64) ALDH1A1KDM4EPARP1TSHRTDP1
SCHEMBL15716703 0.72 PARP1 (0.40) ALDH1A1KDM4ERAB9APARP1ADORA2A
SCHEMBL31484430 0.71 KDM4E (0.50) ALDH1A1KDM4ERAB9APARP1CYP1A2
SCHEMBL21963445 0.69 PTP4A3 (0.63) ALDH1A1KDM4ERAB9APARP1MAPT
SCHEMBL22301763 0.68 PARP1 (0.37) ALDH1A1KDM4EPARP1ADORA2AADORA1
SCHEMBL29196591 0.68 KDM4E (0.56) ALDH1A1KDM4EPARP1ADORA2AADORA1
SCHEMBL3069636 0.68 DPYD (0.42) ALDH1A1KDM4EPARP1ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431381-A Heterocyclic compounds and application thereof 上海艾力斯医药科技股份有限公司 2025-02-14 CN disclosed