SCHEMBL31484489

SCHEMBL31484489

COCCOC1CCC(NC(=O)c2nc(-c3cncs3)nc3ccsc23)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CD38 P28907 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22946910 1.00 CD38 (1.00) CD38
SCHEMBL22933531 0.85 CD38 (1.00) CD38
SCHEMBL28722376 0.85 CD38 (1.00) CD38
SCHEMBL22933165 0.83 CD38 (0.70) CD38
SCHEMBL31266696 0.81 CD38 (0.68) CD38
SCHEMBL31266737 0.81 CD38 (0.68) CD38
SCHEMBL25487215 0.80 CD38 (0.80) CD38
SCHEMBL30230546 0.80 CD38 (0.80) CD38
SCHEMBL32688039 0.78 CD38 (0.64) CD38
SCHEMBL22936146 0.78 CD38 (1.00) CD38

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431323-A Heterobicyclic amides as CD38 inhibitors 贝林格尔·英格海姆国际有限公司 2025-02-14 CN claimed