SCHEMBL31484565

SCHEMBL31484565

COc1ccc2c3ccccc3n(-c3c(C#N)c(-n4c5ccccc5c5ccc(OC)cc54)c(-n4c5ccccc5c5ccc(OC)cc54)c(-n4c5ccccc5c5ccc(OC)cc54)c3C#N)c2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
MAPT P10636 3/20 0.56
HTT P42858 2/20 0.56
MAPK1 P28482 2/20 0.56
LMNA P02545 1/20 0.56
PABPC1 P11940 1/20 0.56
CASP3 P42574 1/20 0.56
NCOA1 Q15788 1/20 0.56
SENP6 Q9GZR1 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NCOA3 Q9Y6Q9 1/20 0.56
ALDH1A1 P00352 4/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MAOA P21397 3/20 0.37
DYRK1A Q13627 3/20 0.37
POLB P06746 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18090930 0.92 KDM4E (0.56) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL25626421 0.88 KDM4E (0.57) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL16175920 0.82 KDM4E (0.43) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL29366189 0.82 KDM4E (0.43) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL29413356 0.82 KDM4E (0.43) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL29682014 0.82 KDM4E (0.43) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL17711114 0.81 MEN1 (0.45) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL29663594 0.81 KDM4E (0.45) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL19954148 0.81 KDM4E (0.45) KDM4EMEN1KMT2AL3MBTL1MAPT
SCHEMBL24871898 0.80 KDM4E (0.36) KDM4EMEN1KMT2AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899174-A Synthesis process of pyridine carbazole compound 南京师范大学 2025-04-29 CN disclosed