Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 14/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22946897 | 0.74 | CD38 (1.00) | CD38 | |
| SCHEMBL30142564 | 0.74 | CD38 (1.00) | CD38 | |
| SCHEMBL22932675 | 0.71 | CD38 (1.00) | CD38YTHDC1 | |
| SCHEMBL29494891 | 0.71 | CD38 (1.00) | CD38YTHDC1 | |
| SCHEMBL29696569 | 0.66 | CD38 (0.54) | CD38CYP3A4KCNH2RORC | |
| SCHEMBL31484700 | 0.65 | CD38 (0.55) | CD38CYP3A4KCNH2GNRHR | |
| SCHEMBL22933159 | 0.64 | CD38 (0.70) | CD38CYP3A4KCNH2YTHDC1 | |
| SCHEMBL29696520 | 0.64 | CD38 (0.70) | CD38CYP3A4KCNH2YTHDC1 | |
| SCHEMBL22932801 | 0.60 | CD38 (1.00) | CD38 | |
| SCHEMBL31484487 | 0.60 | CD38 (1.00) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |