SCHEMBL3148472

SCHEMBL3148472

O=C(Nc1cccc2c(NC(=O)c3ccccc3)cccc12)c1ccccc1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.82
RAB9A P51151 3/20 0.82
CYP1A2 P05177 1/20 0.82
CYP3A4 P08684 1/20 0.82
CYP2D6 P10635 1/20 0.82
CYP2C9 P11712 1/20 0.82
CYP2C19 P33261 1/20 0.82
PARP1 P09874 2/20 0.71
MDM4 O15151 1/20 0.63
TP53 P04637 1/20 0.63
HDAC3 O15379 1/20 0.63
MAPK1 P28482 1/20 0.63
HDAC1 Q13547 1/20 0.63
HDAC2 Q92769 1/20 0.63
POLB P06746 1/20 0.63
HPGD P15428 1/20 0.63
CCR8 P51685 1/20 0.58
KMT2A Q03164 5/20 0.58
MEN1 O00255 4/20 0.58
PKM P14618 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30184438 0.90 NPC1 (1.00) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL4642544 0.90 NPC1 (1.00) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL1110180 0.87 MDM4 (0.73) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL1339026 0.85 NPC1 (0.62) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL11420927 0.85 NPC1 (0.62) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL1339455 0.84 NPC1 (0.60) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL8231826 0.84 NPC1 (0.60) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL12277795 0.84 KMT2A (0.61) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL29124130 0.83 EPHX1 (0.73) NPC1RAB9ACYP1A2CYP3A4CYP2D6
SCHEMBL6054969 0.83 NPC1 (0.60) NPC1RAB9ACYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113316607-B Fiber sheet and method for producing same 花王株式会社 2023-07-28 CN claimed
EP-3910011-A1 FIBER SHEET AND METHOD FOR PRODUCING SAME Kao Corporation (JP) 2021-11-17 EP claimed
CN-113316607-A Fiber sheet and method for producing same 花王株式会社 2021-08-27 CN claimed
EP-3263636-B1 METHOD FOR MANUFACTURING MICROPOROUS FILM AND MICROPOROUS FILM JAPAN STEEL WORKS LTD (JP) 2021-05-12 EP claimed
WO-2020145152-A1 FIBER SHEET AND METHOD FOR PRODUCING SAME 花王株式会社 2020-07-16 WO claimed
US-10633498-B2 Method for manufacturing microporous film and microporous film THE JAPAN STEEL WORKS, LTD. (JP) 2020-04-28 US claimed
US-20180037704-A1 METHOD FOR MANUFACTURING MICROPOROUS FILM AND MICROPOROUS FILM THE JAPAN STEEL WORKS, LTD. (JP) 2018-02-08 US claimed
EP-3263636-A1 METHOD FOR MANUFACTURING MICROPOROUS FILM AND MICROPOROUS FILM The Japan Steel Works, Ltd. (JP) 2018-01-03 EP claimed
WO-2015021948-A1 AGENT FOR NUCLEATION OF POLYOLEFIN AND ELIMINATION OF FOULING IN A GAS PHASE POLYMERISATION REACTOR POLYMER INSTITUTE BRNO, SPOL. S.R.O. (CZ) 2015-02-19 WO claimed
EP-1369221-B9 SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF NEW JAPAN CHEM CO LTD (JP) 2010-12-29 EP claimed
US-20040096744-A1 Extrusion from melt, stretching; mixture of polypropylene and nucleation NEW JAPAN CHEMCIAL CO., LTD. (JP) 2004-05-20 US claimed
EP-1369221-A1 SUCCESSIVELY BIAXIAL-ORIENTED POROUS POLYPROPYLENE FILM AND PROCESS FOR PRODUCTION THEREOF NEW JAPAN CHEMICAL CO.,LTD. (JP) 2003-12-10 EP claimed
US-6235823-B1 CRYSTALLINE POLYPROPLYLENE RESIN AND A BETA-NUCLEATING AGENT, THE BETA-NUCLEATING AGENT BEING A DIAMIDE COMPOUND. NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-05-22 US claimed
EP-0557721-B1 Polypropylene moulded articles with increased -crystal content and bisamides as -nucleating agents. NEW JAPAN CHEM CO LTD (JP) 2000-10-04 EP claimed
US-5973076-A MOLDING; CONTROLLING TEMPERATURE IN PRESENCE OF AN AMIDE COMPOUND NEW JAPAN CHEMICAL CO., LTD. (JP) 1999-10-26 US claimed
EP-0776933-B1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEM CO LTD (JP) 1999-08-04 EP claimed
EP-0776933-A1 Polybutene-1 resin composition and a method of accelerating the crystal transformation NEW JAPAN CHEMICAL CO.,LTD. (JP) 1997-06-04 EP claimed
US-5491188-A ADDING DIAMIDE COMPOUNDS AS NUCLEATING AGENT TO PROPYLENE HOMO-, CO- AND TERPOLYMERS; FILTRATION MEMBRANES, PRINTING SHEETS NEW JAPAN CHEMICAL CO., LTD. (JP) 1996-02-13 US claimed
EP-0632095-A2 Porous stretched article of polypropylene-based resin and process for its preparation NEW JAPAN CHEMICAL CO.,LTD. (JP) 1995-01-04 EP claimed
EP-0557721-A2 Crystalline polypropylene resin composition and amide compounds NEW JAPAN CHEMICAL CO.,LTD. (JP) 1993-09-01 EP claimed