SCHEMBL31484952

SCHEMBL31484952

O=C1CCC(Nc2ccc(NC(=O)CCCCCC(=O)N3CCC(F)(F)CC3)cc2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 16/20 0.47
▸ DDB1 Q16531 15/20 0.47
▸ MAPT P10636 1/20 0.41
▸ HDAC6 Q9UBN7 2/20 0.40
▸ HDAC3 O15379 2/20 0.40
▸ HDAC1 Q13547 2/20 0.40
▸ HDAC2 Q92769 2/20 0.40
▸ HDAC8 Q9BY41 2/20 0.40
▸ HDAC4 P56524 1/20 0.40
▸ HDAC9 Q9UKV0 1/20 0.40
▸ TPSAB1 Q15661 1/20 0.38
▸ TPSD1 Q9BZJ3 1/20 0.38
▸ TPSG1 Q9NRR2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31485004 0.91 CRBN (0.47) CRBNDDB1HDAC6HDAC3HDAC1
SCHEMBL31355917 0.90 CRBN (0.48) CRBNDDB1HDAC3HDAC1HDAC2
SCHEMBL31485017 0.89 DDB1 (0.47) CRBNDDB1HDAC6HDAC3HDAC1
SCHEMBL31356024 0.89 DDB1 (0.47) CRBNDDB1HDAC6HDAC3HDAC1
SCHEMBL31485059 0.88 CRBN (0.43) CRBNDDB1MAPTHDAC6HDAC3
SCHEMBL31356055 0.83 CRBN (0.47) CRBNDDB1
SCHEMBL31746029 0.82 CRBN (0.56) CRBNDDB1HDAC6HDAC3HDAC1
SCHEMBL31745988 0.81 CRBN (0.59) CRBNDDB1HDAC6HDAC3HDAC1
SCHEMBL31485044 0.80 DDB1 (0.56) CRBNDDB1HDAC6HDAC3HDAC1
SCHEMBL31356016 0.80 CRBN (0.50) CRBNDDB1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
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