SCHEMBL31485017

SCHEMBL31485017

O=C1CCC(Nc2ccc(NC(=O)CCCCCCN3CCC(F)(F)CC3)cc2)C(=O)N1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 8/20 0.47
▸ CRBN Q96SW2 8/20 0.47
▸ CACNA1G O43497 2/20 0.41
▸ HDAC3 O15379 2/20 0.40
▸ HDAC1 Q13547 2/20 0.40
▸ HDAC2 Q92769 2/20 0.40
▸ HDAC8 Q9BY41 2/20 0.40
▸ HDAC4 P56524 1/20 0.40
▸ HDAC6 Q9UBN7 1/20 0.40
▸ HDAC9 Q9UKV0 1/20 0.40
▸ HTR1A P08908 1/20 0.40
▸ HTR7 P34969 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31356024 1.00 DDB1 (0.47) DDB1CRBNCACNA1GHDAC3HDAC1
SCHEMBL31485070 0.91 DDB1 (0.48) DDB1CRBNHTR1AHTR7
SCHEMBL31355934 0.91 DDB1 (0.48) DDB1CRBNHTR1AHTR7
SCHEMBL31356213 0.89 DDB1 (0.52) DDB1CRBN
SCHEMBL31484952 0.89 CRBN (0.47) DDB1CRBNHDAC3HDAC1HDAC2
SCHEMBL31355924 0.88 CRBN (0.43) DDB1CRBNCACNA1G
SCHEMBL31484981 0.88 CRBN (0.43) DDB1CRBNCACNA1G
SCHEMBL31485022 0.88 CA1 (0.54) DDB1CRBNHDAC3HDAC1HDAC2
SCHEMBL31356059 0.85 CRBN (0.52) DDB1CRBNHDAC3HDAC1HDAC2
SCHEMBL31356131 0.85 CRBN (0.52) DDB1CRBNHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
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