Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 18/20 | 0.48 |
| ▸ | CBLC | Q9ULV8 | 3/20 | 0.48 |
| ▸ | CBL | P22681 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468182 | 0.93 | CBLB (0.52) | CBLBCBLCCBL | |
| SCHEMBL31485949 | 0.86 | CBLB (0.55) | CBLBCBLCCBL | |
| SCHEMBL31486110 | 0.85 | CBLB (0.53) | CBLBCBLCCBL | |
| SCHEMBL30838238 | 0.83 | CBLB (0.51) | CBLBCBLCCBL | |
| SCHEMBL30838293 | 0.78 | CBLB (0.51) | CBLBCBLCCBL | |
| SCHEMBL30838133 | 0.78 | CBLB (0.51) | CBLBCBLCCBL | |
| SCHEMBL30838192 | 0.77 | CBLB (0.50) | CBLBCBLCCBL | |
| SCHEMBL31485875 | 0.77 | CBLB (0.56) | CBLBCBLCCBL | |
| SCHEMBL30838257 | 0.77 | CBLB (0.56) | CBLBCBLCCBL | |
| SCHEMBL31485957 | 0.76 | CBLB (0.53) | CBLBCBLCCBL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025076299-A1 | CBL-B INHIBITORS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-04-10 | — | — | WO | disclosed |