P-Nitrophenol

P-Nitrophenol

SCHEMBL3148668

Cc1ccc(O)cc1.O=[N+]([O-])c1ccc(O)cc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.78
HSD17B10 Q99714 2/20 0.78
MAOA P21397 1/20 0.51
MAOB P27338 1/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
POLB P06746 1/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 2/20 0.50
PKM P14618 1/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
GFER P55789 1/20 0.50
CES1 P23141 1/20 0.48
BCHE P06276 1/20 0.47
CYTH2 Q99418 1/20 0.47
PTGS1 P23219 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Cresol SCHEMBL27506994 1.00 ACHE (0.78) ACHEHSD17B10MAOAMAOBMEN1
SCHEMBL15000299 0.89 ACHE (0.62) ACHEHSD17B10MAOAMAOBMEN1
P-Nitrophenol SCHEMBL1115712 0.89 HSD17B10 (0.58) ACHEHSD17B10MEN1KMT2AALDH1A1
4-Nitrotoluene SCHEMBL28795853 0.89 HSD17B10 (0.90) ACHEHSD17B10MAOAMAOBMEN1
4-Nitrotoluene SCHEMBL2484690 0.89 ACHE (1.00) ACHEHSD17B10MAOAMAOBKMT2A
4-Nitrotoluene SCHEMBL73252 0.89 ACHE (1.00) ACHEHSD17B10MAOAMAOBKMT2A
P-Nitrophenol SCHEMBL11048842 0.89 CES1 (0.58) ACHEHSD17B10MEN1KMT2AALDH1A1
P-Nitrophenol SCHEMBL29806213 0.89 CES1 (0.58) ACHEHSD17B10MEN1KMT2AALDH1A1
P-Nitrophenol SCHEMBL1839 0.89 CES1 (0.58) ACHEHSD17B10MEN1KMT2AALDH1A1
4-Nitrotoluene SCHEMBL28384838 0.86 ACHE (0.86) ACHEHSD17B10MAOAMAOBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754145-B2 Fluorphore embedded/incorporating/bridged periodic mesoporous organosilicas as recognition photo-decontamination catalysts THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-07-13 US disclosed
US-7749438-B2 Fluorophore embedded/incorporating/bridged periodic mesoporous organosilicas as recognition elements for optical sensors THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-07-06 US disclosed
US-20100081205-A1 FLUOROPHORE EMBEDDED/INCORPORATING/BRIDGED PERIODIC MESOPOROUS ORGANOSILICAS AS RECOGNITION ELEMENTS FOR OPTICAL SENSORS NAVE, USA AS REPRESENTED BY THE SECRETARY OF THE, THE 2010-04-01 US disclosed
US-20070073095-A1 FLUORPHORE EMBEDDED/INCORPORATING/BRIDGED PERIODIC MESOPOROUS ORGANOSILICAS AS RECOGNITION PHOTO-DECONTAMINATION CATALYSTS USA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE 2007-03-29 US disclosed