SCHEMBL31487009

SCHEMBL31487009

Fc1ccc2c(c1)cc1n2CCCOC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 6/20 0.43
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
PIK3CA P42336 3/20 0.34
PIK3CB P42338 3/20 0.34
PIK3CG P48736 3/20 0.34
PIK3CD O00329 1/20 0.34
PER2 O15055 3/20 0.33
CRY2 Q49AN0 2/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18202354 0.91 SIGMAR1 (0.42) SIGMAR1HTR2AHTR2CPIK3CAPIK3CB
SCHEMBL31487049 0.80 HTR2A (0.49) SIGMAR1HTR2AHTR2C
SCHEMBL18202191 0.79 SIGMAR1 (0.48) SIGMAR1HTR2AHTR2CPER2CRY2
SCHEMBL18202248 0.78 HTR2A (0.38) SIGMAR1HTR2AHTR2CPIK3CAPIK3CB
SCHEMBL24916793 0.78 SIGMAR1 (0.50) SIGMAR1HTR2AHTR2CPER2CRY2
SCHEMBL31486985 0.77 SIGMAR1 (0.41) SIGMAR1HTR2AHTR2CPIK3CAPIK3CB
SCHEMBL18527235 0.73 HTR2A (0.56) HTR2AHTR2CPIK3CAPIK3CBPIK3CG
SCHEMBL8133155 0.72 MAPT (0.38) HTR2AHTR2CPIK3CAKDM4EALDH1A1
SCHEMBL31487256 0.69 HTR2A (0.51) SIGMAR1HTR2AHTR2CKDM4E
SCHEMBL1520653 0.69 HTR2A (0.51) SIGMAR1HTR2AHTR2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed