SCHEMBL31487330

SCHEMBL31487330

O=C(O)c1c2n(c3ccc(F)cc13)CCC2

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.57
GAA P10253 2/20 0.49
MAPK1 P28482 1/20 0.49
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 1/20 0.44
KDM4E B2RXH2 2/20 0.44
PER2 O15055 3/20 0.39
CRY2 Q49AN0 2/20 0.39
USP14 P54578 1/20 0.38
PTGDR2 Q9Y5Y4 1/20 0.37
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
SRC P12931 1/20 0.36
RORC P51449 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31486817 1.00 KMT2A (0.57) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL31486784 0.94 KMT2A (0.51) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL31486983 0.84 KMT2A (0.40) KMT2AGAAMAPK1ALDH1A1PER2
SCHEMBL31486876 0.83 KMT2A (0.40) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL31487022 0.81 GAA (0.77) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL31487208 0.80 GAA (0.41) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL31486786 0.79 HTR2A (0.52) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL7321799 0.79 HTR2A (0.52) KMT2AGAAMAPK1ALDH1A1ALOX15
SCHEMBL31486818 0.79 KDM5A (0.36) KMT2AALDH1A1KDM4EPER2CRY2
SCHEMBL31487166 0.76 GAA (0.55) KMT2AGAAMAPK1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed