SCHEMBL31487208

SCHEMBL31487208

N=C(NO)c1c2n(c3ccc(F)cc13)CCC2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
HDAC1 Q13547 7/20 0.36
HDAC6 Q9UBN7 7/20 0.36
PER2 O15055 3/20 0.34
CRY2 Q49AN0 2/20 0.34
HDAC3 O15379 4/20 0.32
HDAC10 Q969S8 4/20 0.32
HDAC8 Q9BY41 4/20 0.32
HDAC2 Q92769 2/20 0.32
USP14 P54578 1/20 0.32
HDAC4 P56524 3/20 0.31
HDAC7 Q8WUI4 3/20 0.31
HDAC9 Q9UKV0 3/20 0.31
HDAC5 Q9UQL6 3/20 0.31
HDAC11 Q96DB2 2/20 0.31
HTR6 P50406 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31487078 0.81 PER2 (0.38) HDAC1HDAC6PER2CRY2
SCHEMBL31486769 0.81 HTR2A (0.43) GAAMAPK1KMT2AHDAC1HDAC6
SCHEMBL31487248 0.81 HTR2A (0.43) GAAMAPK1KMT2AHDAC1HDAC6
SCHEMBL31486817 0.80 KMT2A (0.57) GAAMAPK1KMT2AALDH1A1ALOX15
SCHEMBL31487330 0.80 KMT2A (0.57) GAAMAPK1KMT2AALDH1A1ALOX15
SCHEMBL31486784 0.75 KMT2A (0.51) GAAMAPK1KMT2AALDH1A1ALOX15
SCHEMBL18202165 0.73 HTR2C (0.41) GAAMAPK1KMT2AALDH1A1ALOX15
SCHEMBL31487022 0.73 GAA (0.77) GAAMAPK1KMT2AALDH1A1ALOX15
SCHEMBL19960993 0.72 PER2 (0.41) GAAMAPK1PER2CRY2HTR6
SCHEMBL31486870 0.69 CHRNA7 (0.47) GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025077825-A1 METHODS AND COMPOSITIONS FOR TREATING CARDIO-PULMONARY DISORDERS FAUNA BIO INCORPORATED (US) 2025-04-17 WO disclosed