Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 18/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 17/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965649 | 0.90 | CRBN (0.47) | CRBNDDB1HTR1AADRA1DADRA1A | |
| SCHEMBL30965791 | 0.85 | CRBN (0.47) | CRBNDDB1IKZF3 | |
| SCHEMBL30965695 | 0.84 | CRBN (0.42) | CRBNDDB1IKZF3 | |
| SCHEMBL30965666 | 0.82 | CRBN (0.44) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL30965595 | 0.82 | CRBN (0.57) | CRBNDDB1 | |
| SCHEMBL30965703 | 0.81 | CRBN (0.42) | CRBNDDB1DRD2 | |
| SCHEMBL30965564 | 0.81 | CRBN (0.48) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL30965835 | 0.81 | CRBN (0.42) | CRBNDDB1DRD2 | |
| SCHEMBL30915166 | 0.78 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL27367035 | 0.77 | DDB1 (0.47) | CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790057-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2025-04-08 | — | — | CN | disclosed |