SCHEMBL30965703

SCHEMBL30965703

CC(C)(C)OC(=O)NC1CCN(CCN2CCN(c3cc(F)c(NC4CCC(=O)NC4=O)cc3F)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 10/20 0.42
DDB1 Q16531 9/20 0.42
DRD2 P14416 5/20 0.42
DRD3 P35462 2/20 0.42
KCNA3 P22001 1/20 0.40
PARP1 P09874 1/20 0.38
PARP2 Q9UGN5 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30965558 0.94 DRD2 (0.45) CRBNDDB1DRD2DRD3KCNA3
SCHEMBL30965618 0.94 CRBN (0.45) CRBNDDB1DRD2DRD3KCNA3
SCHEMBL30965799 0.93 DRD2 (0.44) CRBNDDB1DRD2DRD3KCNA3
SCHEMBL30915142 0.90 CRBN (0.49) CRBNDDB1DRD2DRD3KCNA3
SCHEMBL30965827 0.90 DDB1 (0.43) CRBNDDB1DRD2DRD3KCNA3
SCHEMBL30965523 0.88 CRBN (0.46) CRBNDDB1DRD2
SCHEMBL31712312 0.87 CRBN (0.47) CRBNDDB1DRD2DRD3KCNA3
SCHEMBL30965552 0.85 CRBN (0.43) CRBNDDB1DRD2DRD3
SCHEMBL27225107 0.84 DRD2 (0.48) CRBNDDB1DRD2DRD3
SCHEMBL30981399 0.84 DRD2 (0.53) CRBNDDB1DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658658-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND Uppthera, Inc. (KR) 2025-12-10 EP disclosed
WO-2024162828-A1 NOVEL PLK1 DEGRADATION INDUCING COMPOUND UPPTHERA, INC. (KR) 2024-08-08 WO disclosed