Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763439 | 0.88 | CYP2C9 (0.41) | ESR2CYP2C9ESR1POLBMEN1 | |
| SCHEMBL31042568 | 0.81 | ESR2 (0.64) | ESR2CYP2C9ESR1KDM1APOLB | |
| SCHEMBL14299432 | 0.77 | KDM1A (0.45) | ESR2CYP2C9ESR1KDM1AMEN1 | |
| SCHEMBL536531 | 0.77 | CXCR3 (0.44) | ESR2CYP2C9ESR1CYP3A4TEAD1 | |
| SCHEMBL23040780 | 0.77 | CYP2C9 (0.36) | ESR2CYP2C9ESR1POLBMEN1 | |
| SCHEMBL25181452 | 0.77 | KDM1A (0.45) | ESR2CYP2C9ESR1KDM1AMAPT | |
| SCHEMBL3308965 | 0.76 | MAOB (0.41) | CYP2C9KDM1ACYP3A4HSD17B10LMNA | |
| SCHEMBL28593750 | 0.75 | HTR2A (0.45) | CYP3A4ALDH1A1HSD17B10CA14CA12 | |
| SCHEMBL2710584 | 0.75 | GAA (0.42) | ESR2CYP2C9ESR1KDM1APOLB | |
| SCHEMBL1516055 | 0.74 | ESR2 (0.48) | ESR2CYP2C9ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12049440-B2 | Processes for preparing calixarenes | SI GROUP, INC. (US) | 2024-07-30 | — | — | US | disclosed |
| US-20220177397-A1 | PROCESSES FOR PREPARING CALIXARENES | SI GROUP, INC. | 2022-06-09 | — | — | US | disclosed |
| CN-111646951-B | Organic compound, electronic element, and electronic device | 陕西莱特光电材料股份有限公司 | 2022-01-28 | — | — | CN | disclosed |
| US-11225450-B2 | Processes for preparing calixarenes | SI GROUP, INC. (US) | 2022-01-18 | — | — | US | disclosed |
| CN-111662241-B | Organic compound, electronic element, and electronic device | 陕西莱特光电材料股份有限公司 | 2021-09-03 | — | — | CN | disclosed |
| US-11072572-B2 | Processes for preparing calixarenes | SI GROUP, INC. (US) | 2021-07-27 | — | — | US | disclosed |
| CN-112441930-A | Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus | 株式会社半导体能源研究所 | 2021-03-05 | — | — | CN | disclosed |
| US-20210047253-A1 | PROCESSES FOR PREPARING CALIXARENES | SI GROUP, INC. | 2021-02-18 | — | — | US | disclosed |
| US-20210017109-A1 | PROCESSES FOR PREPARING CALIXARENES | SI GROUP, INC. | 2021-01-21 | — | — | US | disclosed |
| US-10843990-B2 | Processes for preparing calix[4]arenes from calix[8]arenes | SI GROUP, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-8642603-B2 | Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof | SANOFI (FR) | 2014-02-04 | — | — | US | disclosed |
| US-20100075994-A1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-25 | — | — | US | disclosed |
| EP-1192122-B1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2003-10-22 | — | — | EP | disclosed |
| US-6482986-B1 | Benzene derivatives, preparation method and pharmaceutical compositions containing same | SANOFI-SYNTHELABO (FR) | 2002-11-19 | — | — | US | disclosed |
| EP-1192122-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076953-A1 | BENZENE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI-SYNTHELABO (FR) | 2000-12-21 | — | — | WO | disclosed |
| US-4013719-A | ANTILIPEMIC, ANTIALLERGEN | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-4000183-A | ANTIALLERGENS AND HYPOLIPIDAEMIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-4000144-A | HYPOLIPIDAEMIC AGENTS AND ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3933835-A | ANTIALLERGENS, HYPOLIPIDAEMIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047253-A1 | PROCESSES FOR PREPARING CALIXARENES | CALU, CALD1, CALR | ESR2 2472/4885CYP2C9 269/4885ESR1 1107/4885 |
| US-10843990-B2 | Processes for preparing calix[4]arenes from calix[8]arenes | CANX, CALD1, CALU | ESR2 2783/4885CYP2C9 210/4885ESR1 903/4885 |
| US-11225450-B2 | Processes for preparing calixarenes | CALU, CALD1, CALR | ESR2 2472/4885CYP2C9 269/4885ESR1 1107/4885 |
| US-20100075994-A1 | SUBSTITUTED DIHYDRO AND TETRAHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | GRM2, GRM1, GRIN2C | ESR2 491/4885CYP2C9 690/4885ESR1 699/4885 |
| US-11072572-B2 | Processes for preparing calixarenes | CALU, CALD1, CALR | ESR2 2472/4885CYP2C9 269/4885ESR1 1107/4885 |
| US-20220177397-A1 | PROCESSES FOR PREPARING CALIXARENES | CALU, CALD1, CALR | ESR2 2472/4885CYP2C9 269/4885ESR1 1107/4885 |
| US-20210017109-A1 | PROCESSES FOR PREPARING CALIXARENES | CALU, CALD1, CALR | ESR2 2472/4885CYP2C9 269/4885ESR1 1107/4885 |
| US-12049440-B2 | Processes for preparing calixarenes | CALU, CALD1, CALR | ESR2 2472/4885CYP2C9 269/4885ESR1 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.