Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 10/20 | 0.73 |
| ▸ | FLT4 | P35916 | 8/20 | 0.73 |
| ▸ | KIT | P10721 | 6/20 | 0.73 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.73 |
| ▸ | CSF1R | P07333 | 1/20 | 0.73 |
| ▸ | KDR | P35968 | 8/20 | 0.71 |
| ▸ | AURKB | Q96GD4 | 9/20 | 0.65 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.61 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.60 |
| ▸ | AURKC | Q9UQB9 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213097 | 0.84 | CSF1R (1.00) | FLT3FLT4KITPDGFRBCSF1R | |
| SCHEMBL25564419 | 0.84 | CSF1R (1.00) | FLT3FLT4KITPDGFRBCSF1R | |
| SCHEMBL13256127 | 0.81 | NTRK1 (0.71) | FLT3FLT4KITPDGFRBCSF1R | |
| SCHEMBL3590032 | 0.80 | FLT3 (0.90) | FLT3FLT4KITPDGFRBCSF1R | |
| SCHEMBL3590029 | 0.80 | FLT3 (0.90) | FLT3FLT4KITPDGFRBCSF1R | |
| SCHEMBL15327925 | 0.78 | AURKB (1.00) | FLT3FLT4KITPDGFRBKDR | |
| SCHEMBL15327923 | 0.78 | AURKB (1.00) | FLT3FLT4KITPDGFRBKDR | |
| SCHEMBL3594888 | 0.78 | NTRK1 (0.79) | FLT3FLT4KITPDGFRBKDR | |
| SCHEMBL3603754 | 0.78 | FLT3 (0.89) | FLT3FLT4KITPDGFRBCSF1R | |
| SCHEMBL3594887 | 0.78 | NTRK1 (0.79) | FLT3FLT4KITPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025089370-A1 | COMPOUNDS AS CSF1R INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-05-01 | — | — | WO | disclosed |