Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 14/20 | 1.00 |
| ▸ | FLT4 | P35916 | 6/20 | 0.68 |
| ▸ | FLT3 | P36888 | 6/20 | 0.68 |
| ▸ | KIT | P10721 | 5/20 | 0.68 |
| ▸ | KDR | P35968 | 5/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29213097 | 1.00 | CSF1R (1.00) | CSF1RFLT4FLT3KITKDR | |
| SCHEMBL25564657 | 0.91 | CSF1R (0.84) | CSF1RFLT4FLT3KITKDR | |
| SCHEMBL25564615 | 0.87 | CSF1R (1.00) | CSF1R | |
| SCHEMBL29213101 | 0.87 | CSF1R (1.00) | CSF1R | |
| SCHEMBL29213098 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL25564656 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL31487736 | 0.84 | FLT3 (0.73) | CSF1RFLT4FLT3KITKDR | |
| SCHEMBL29213100 | 0.83 | CSF1R (0.79) | CSF1R | |
| SCHEMBL25564654 | 0.83 | CSF1R (0.79) | CSF1R | |
| SCHEMBL25185189 | 0.82 | CSF1R (1.00) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999221-A | 6-substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2022-02-01 | — | — | CN | claimed |
| CN-113999221-B | 6-substituted indolone derivative and medical application thereof | 南京中医药大学 | 2024-04-05 | — | — | CN | disclosed |
| WO-2023078207-A1 | 6-POSITION-SUBSTITUTED INDOLINONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 南京中医药大学 | 2023-05-11 | — | — | WO | disclosed |
| CN-113999221-A | 6-substituted indolone derivative, preparation method and medical application thereof | 南京中医药大学 | 2022-02-01 | — | — | CN | disclosed |