Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21972573 | 0.86 | ALDH1A1 (0.76) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5061957 | 0.86 | ALDH1A1 (0.75) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13384689 | 0.84 | ALDH1A1 (0.73) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10502377 | 0.84 | KMT2A (1.00) | HSD17B10KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL5271531 | 0.84 | ALDH1A1 (0.71) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2605790 | 0.83 | KDM4E (0.70) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9442187 | 0.82 | ALDH1A1 (0.68) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14338571 | 0.81 | ALDH1A1 (0.68) | HSD17B10KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9958465 | 0.81 | KMT2A (0.81) | HSD17B10KDM4EALDH1A1KMT2ATSHR | |
| SCHEMBL25389264 | 0.80 | ALDH1A1 (0.67) | HSD17B10KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250115573-A1 | PYRIDAZINE-BASED PYRIDINE DERIVATIVES AS BIOLOGICALLY ACTIVE AGENTS | IMRAN MOHD (SA) | 2025-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250115573-A1 | PYRIDAZINE-BASED PYRIDINE DERIVATIVES AS BIOLOGICALLY ACTIVE AGENTS | HRH4, HRH3, CBR3 | HSD17B10 2127/4885KDM4E 3361/4885ALDH1A1 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.