SCHEMBL31488977

SCHEMBL31488977

CC(C)(O)C(=O)Nc1ccc(NC(=O)N2Cc3cc(F)cnc3C2)cc1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 19/20 0.49
MOGAT2 Q3SYC2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488873 0.88 NAMPT (0.46) NAMPT
SCHEMBL31488911 0.86 NAMPT (0.52) NAMPT
SCHEMBL31488807 0.84 NAMPT (0.51) NAMPT
SCHEMBL31488809 0.83 NAMPT (0.67) NAMPT
SCHEMBL31488867 0.82 NAMPT (0.68) NAMPT
SCHEMBL31488876 0.80 MEN1 (0.53) NAMPT
SCHEMBL31489000 0.80 NAMPT (0.51) NAMPTMOGAT2
SCHEMBL31488825 0.79 NAMPT (0.76) NAMPT
SCHEMBL31488832 0.78 NAMPT (0.65) NAMPT
Hydrochloric Acid SCHEMBL31489048 0.78 NAMPT (0.64) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed