SCHEMBL31489000

SCHEMBL31489000

CC(C)(O)C(=O)Nc1ccc(NC(=O)N2Cc3cc(F)cc(F)c3C2)cc1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 17/20 0.51
MOGAT2 Q3SYC2 3/20 0.45
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
TAS1R2 Q8TE23 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488819 0.85 NAMPT (0.51) NAMPT
SCHEMBL31489085 0.83 TAS1R3 (0.46) NAMPTTAS1R3TAS1R1TAS1R2
SCHEMBL31489014 0.82 NAMPT (0.70) NAMPT
SCHEMBL31488861 0.81 NAMPT (0.71) NAMPT
SCHEMBL31488977 0.80 NAMPT (0.49) NAMPTMOGAT2
SCHEMBL31488935 0.79 MEN1 (0.55) NAMPTTAS1R3TAS1R1TAS1R2
SCHEMBL31488961 0.78 NAMPT (0.78) NAMPT
SCHEMBL31488795 0.77 NAMPT (0.67) NAMPT
Hydrochloric Acid SCHEMBL31488963 0.76 NAMPT (0.66) NAMPT
SCHEMBL31488821 0.76 NAMPT (0.52) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed