SCHEMBL31488992

SCHEMBL31488992

CC(C)(C)OC(=O)NS(=O)(=O)N1CC=C(c2ccc(NC(=O)N3Cc4cccc(F)c4C3)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488944 0.90 NAMPT (0.56) NAMPT
SCHEMBL31488823 0.85 NAMPT (0.56) NAMPT
SCHEMBL31489075 0.84 NAMPT (0.79) NAMPT
SCHEMBL31489060 0.84 NAMPT (0.56) NAMPT
SCHEMBL31489053 0.84 NAMPT (0.61) NAMPT
SCHEMBL31488922 0.83 NAMPT (0.57) NAMPT
SCHEMBL31488864 0.82 NAMPT (0.66) NAMPT
SCHEMBL31488938 0.82 NAMPT (0.50) NAMPT
SCHEMBL31488818 0.77 NAMPT (0.62) NAMPT
SCHEMBL31489159 0.76 NAMPT (0.46) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed