Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489051 | 0.84 | NAMPT (0.44) | NAMPTLIPEGAANPSR1MMP2 | |
| SCHEMBL31488923 | 0.81 | NAMPT (0.68) | NAMPTLIPEGAANPSR1ALDH1A1 | |
| SCHEMBL31489083 | 0.81 | CCNT1 (0.47) | NAMPTCCNT1CDK9MMP2MMP3 | |
| SCHEMBL31489049 | 0.77 | CCNT1 (0.45) | NAMPTCCNT1CDK9MMP2MMP3 | |
| SCHEMBL31488837 | 0.77 | NAMPT (0.66) | NAMPTGAANPSR1ALDH1A1MAPT | |
| SCHEMBL31488992 | 0.76 | NAMPT (0.56) | NAMPT | |
| SCHEMBL31489060 | 0.76 | NAMPT (0.56) | NAMPT | |
| SCHEMBL31488823 | 0.76 | NAMPT (0.56) | NAMPTCCNT1CDK9 | |
| SCHEMBL31488864 | 0.76 | NAMPT (0.66) | NAMPT | |
| SCHEMBL6815441 | 0.74 | ALDH1A1 (0.69) | LIPEGAANPSR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |