Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.66 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31488909 | 0.88 | NAMPT (0.52) | NAMPTCCR1CYP3A4CYP2C9GAA | |
| SCHEMBL31488900 | 0.86 | NAMPT (0.68) | NAMPTCCR1CYP3A4CYP2C9GAA | |
| SCHEMBL25567301 | 0.86 | NAMPT (0.69) | NAMPTCCR1GAANPSR1ALDH1A1 | |
| SCHEMBL1988842 | 0.82 | NAMPT (0.60) | NAMPTGAANPSR1ALDH1A1MAPT | |
| SCHEMBL29537824 | 0.82 | NAMPT (0.60) | NAMPTGAANPSR1ALDH1A1MAPT | |
| SCHEMBL1988843 | 0.82 | NAMPT (0.60) | NAMPTGAANPSR1ALDH1A1MAPT | |
| SCHEMBL29739410 | 0.82 | ALDH1A1 (0.62) | GAANPSR1ALDH1A1MAPTKMT2A | |
| SCHEMBL31489108 | 0.80 | ALDH1A1 (0.49) | NAMPTGAANPSR1ALDH1A1MAPT | |
| SCHEMBL3704659 | 0.80 | NAMPT (1.00) | NAMPTCYP3A4CYP2C9 | |
| SCHEMBL29177237 | 0.79 | ALDH1A1 (0.59) | GAANPSR1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |