SCHEMBL31489106

SCHEMBL31489106

CN(C(=O)NCC(C)(C)O)C12CCC(c3ccc(NC(=O)N4Cc5ccc(F)cc5C4)cc3)(CC1)CC2

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488793 0.87 NAMPT (0.53) NAMPT
SCHEMBL31488810 0.87 NAMPT (0.68) NAMPT
SCHEMBL31488808 0.84 NAMPT (0.67) NAMPT
SCHEMBL31488890 0.82 NAMPT (0.69) NAMPT
SCHEMBL31489140 0.81 NAMPT (0.53) NAMPT
SCHEMBL31488967 0.81 NAMPT (0.60) NAMPT
SCHEMBL31489492 0.81 NAMPT (0.58) NAMPT
SCHEMBL31488836 0.79 NAMPT (0.68) NAMPT
SCHEMBL31489035 0.79 NAMPT (0.55) NAMPT
SCHEMBL31489094 0.79 NAMPT (0.60) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed