Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PTGIR | P43119 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24029363 | 0.91 | SIGMAR1 (0.47) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL19357853 | 0.91 | SIGMAR1 (0.47) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL24029365 | 0.89 | SIGMAR1 (0.44) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL29710313 | 0.83 | SIGMAR1 (0.44) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL19357722 | 0.83 | SIGMAR1 (0.44) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL12616547 | 0.79 | SIGMAR1 (0.61) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL3606181 | 0.79 | SIGMAR1 (0.53) | SIGMAR1SMN1; SMN2PTGIRMAPTALDH1A1 | |
| SCHEMBL21522072 | 0.78 | KMT2A (0.47) | SIGMAR1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL24761528 | 0.78 | ACACB (0.51) | SIGMAR1SMN1; SMN2PTGIRMAPTCHKA | |
| SCHEMBL1043952 | 0.76 | SIGMAR1 (0.85) | SIGMAR1SMN1; SMN2PTGIRALDH1A1CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |