SCHEMBL31489112

SCHEMBL31489112

CC(C)(O)CS(=O)(=O)N1CC=C(c2ccc(NC(=O)N3Cc4cc(F)cc(F)c4C3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NAMPT P43490 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31488865 0.87 NAMPT (0.51) NAMPT
SCHEMBL31489061 0.85 NAMPT (0.54) NAMPT
SCHEMBL31488861 0.84 NAMPT (0.71) NAMPT
SCHEMBL31488945 0.82 NAMPT (0.57) NAMPT
SCHEMBL31489130 0.80 NAMPT (0.72) NAMPT
SCHEMBL31489053 0.75 NAMPT (0.61) NAMPT
SCHEMBL31488877 0.74 NAMPT (0.61) NAMPT
SCHEMBL31489000 0.74 NAMPT (0.51) NAMPT
SCHEMBL31488803 0.74 NAMPT (0.69) NAMPT
SCHEMBL31489015 0.74 NAMPT (0.72) NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072437-A1 HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ALPHINA THERAPEUTICS, INC. (US) 2025-04-03 WO disclosed