Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31488978 | 0.87 | NAMPT (0.57) | NAMPTTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL31488895 | 0.86 | NAMPT (0.56) | NAMPT | |
| SCHEMBL31489031 | 0.86 | NAMPT (0.56) | NAMPT | |
| SCHEMBL31488910 | 0.81 | TAS1R3 (0.61) | NAMPTTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL31488874 | 0.80 | NAMPT (0.64) | NAMPTTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL31488982 | 0.79 | NAMPT (0.45) | NAMPTNPC1RAB9A | |
| SCHEMBL10226370 | 0.79 | NPC1 (0.78) | NAMPTTAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL31489030 | 0.78 | MAPK1 (0.36) | NAMPTTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL31488989 | 0.75 | NAMPT (0.57) | NAMPT | |
| SCHEMBL31488919 | 0.75 | NAMPT (0.57) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |