SCHEMBL31489216 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CREBBP	Q92793	10/20	0.45

▸	CLK1	P49759	1/20	0.39

▸	DYRK1A	Q13627	1/20	0.39

▸	GPR55	Q9Y2T6	1/20	0.38

▸	CYP11B2	P19099	2/20	0.37

▸	CYP11B1	P15538	1/20	0.37

▸	JAK2	O60674	2/20	0.36

▸	MET	P08581	1/20	0.36

▸	CYP17A1	P05093	1/20	0.34

▸	BRD4	O60885	1/20	0.34

▸	JAK1	P23458	1/20	0.34

▸	TYK2	P29597	1/20	0.34

▸	JAK3	P52333	1/20	0.34

▸	KIT	P10721	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31489577	1.00	CREBBP (0.45)	CREBBPCLK1DYRK1AGPR55CYP11B2
SCHEMBL31489871	0.85	CREBBP (0.45)	CREBBPCLK1DYRK1AGPR55JAK2
SCHEMBL31489286	0.85	CREBBP (0.45)	CREBBPCLK1DYRK1AGPR55JAK2
SCHEMBL31489474	0.76	CREBBP (0.46)	CREBBPCLK1DYRK1AGPR55CYP11B2
SCHEMBL31489417	0.76	CREBBP (0.46)	CREBBPCLK1DYRK1AGPR55CYP11B2
SCHEMBL31489459	0.75	CREBBP (0.42)	CREBBPGPR55CYP17A1BRD4
SCHEMBL31489526	0.75	CREBBP (0.42)	CREBBPGPR55CYP17A1BRD4
SCHEMBL31489770	0.74	CREBBP (0.39)	CREBBPCLK1DYRK1AGPR55JAK2
SCHEMBL31489699	0.74	CREBBP (0.39)	CREBBPCLK1DYRK1AGPR55JAK2
SCHEMBL1691594	0.73	CYP11B2 (0.46)	CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2025072395-A1	TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS	BRISTOL-MYERS SQUIBB COMPANY (US)	2025-04-03	—	—	WO	disclosed