Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.57 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | GRM1 | Q13255 | 11/20 | 0.53 |
| ▸ | GRM5 | P41594 | 10/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.50 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.46 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.46 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908091 | 0.96 | NAMPT (0.60) | NAMPTPDK4GRM1GRM5NR1H2 | |
| SCHEMBL29227506 | 0.96 | NAMPT (0.60) | NAMPTPDK4GRM1GRM5NR1H2 | |
| SCHEMBL25233965 | 0.89 | NAMPT (0.53) | NAMPTPDK4GRM1GRM5NR1H2 | |
| SCHEMBL31110456 | 0.86 | NAMPT (0.58) | NAMPTPDK4GRM1GRM5TNK2 | |
| SCHEMBL29227507 | 0.86 | NAMPT (0.49) | NAMPTPDK4GRM1GRM5NR1H2 | |
| SCHEMBL19989639 | 0.86 | NAMPT (0.67) | NAMPTPDK4GRM1GRM5TNK2 | |
| SCHEMBL8912847 | 0.85 | NAMPT (0.63) | NAMPTPDK4GRM1GRM5TNK2 | |
| SCHEMBL2239831 | 0.85 | NAMPT (0.66) | NAMPTPDK4GRM1GRM5TNK2 | |
| SCHEMBL5548551 | 0.85 | NAMPT (0.59) | NAMPTPDK4GRM1GRM5TNK2 | |
| SCHEMBL904049 | 0.84 | NAMPT (0.61) | NAMPTPDK4GRM1GRM5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072437-A1 | HETEROARYL COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | ALPHINA THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |