Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489275 | 0.97 | — | — | |
| SCHEMBL31489730 | 0.94 | ROCK2 (0.31) | — | |
| SCHEMBL31489623 | 0.91 | ROCK2 (0.31) | — | |
| SCHEMBL31489638 | 0.89 | ROCK2 (0.32) | — | |
| SCHEMBL31489475 | 0.88 | — | — | |
| SCHEMBL31489561 | 0.88 | PIK3CG (0.37) | JAK2JAK1TYK2JAK3PDE10A | |
| SCHEMBL31489602 | 0.85 | PIK3CG (0.37) | JAK1 | |
| SCHEMBL31489635 | 0.83 | ROCK2 (0.31) | — | |
| SCHEMBL31489796 | 0.83 | ROCK2 (0.31) | — | |
| SCHEMBL31489457 | 0.83 | MAPK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |