SCHEMBL31489295

SCHEMBL31489295

CC(c1ccc(F)cc1)n1cc(-c2cc(F)cc(-c3ccn4nc(N)nc4c3)c2F)cn1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CREBBP Q92793 3/20 0.38
PIK3CG P48736 11/20 0.38
PIK3CD O00329 9/20 0.38
RIPK1 Q13546 3/20 0.37
NTRK1 P04629 1/20 0.36
PAK4 O96013 1/20 0.34
JAK1 P23458 1/20 0.34
PIK3CA P42336 1/20 0.34
PIK3CB P42338 1/20 0.34
CSNK1A1 P48729 1/20 0.34
AAK1 Q2M2I8 1/20 0.34
PIP4K2C Q8TBX8 1/20 0.34
CSNK1G1 Q9HCP0 1/20 0.34
MET P08581 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489822 1.00 CREBBP (0.38) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489701 0.93 RIPK1 (0.40) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489633 0.93 RIPK1 (0.40) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489312 0.93 PIK3CG (0.41) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489372 0.93 RIPK1 (0.40) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489740 0.93 RIPK1 (0.40) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489801 0.90 CREBBP (0.39) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489359 0.90 CREBBP (0.39) CREBBPPIK3CGPIK3CDRIPK1NTRK1
SCHEMBL31489813 0.88 PIK3CG (0.41) CREBBPPIK3CGPIK3CDRIPK1PAK4
SCHEMBL31489199 0.88 PIK3CG (0.41) CREBBPPIK3CGPIK3CDRIPK1PAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed