Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 2/20 | 0.61 |
| ▸ | JAK3 | P52333 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ATIC | P31939 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134249 | 1.00 | KDM4E (0.64) | KDM4EHSP90AA1HSP90AB1EGFRJAK3 | |
| SCHEMBL13134397 | 0.88 | EGFR (0.59) | KDM4EHSP90AA1HSP90AB1EGFRJAK3 | |
| SCHEMBL493877 | 0.79 | DEGS1 (0.60) | KDM4EHSP90AA1HSP90AB1EGFRNPC1 | |
| SCHEMBL493878 | 0.79 | DEGS1 (0.60) | KDM4EHSP90AA1HSP90AB1EGFRNPC1 | |
| SCHEMBL32681801 | 0.79 | NPC1 (0.59) | PTPN1PTPN11NPC1RAB9ATGM2 | |
| SCHEMBL20609244 | 0.79 | NPC1 (0.59) | PTPN1PTPN11NPC1RAB9ATGM2 | |
| SCHEMBL8515227 | 0.78 | KDM4E (0.70) | KDM4EHSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL29186499 | 0.77 | KDM4E (0.68) | KDM4EHSP90AA1HSP90AB1EGFRNPC1 | |
| SCHEMBL13134248 | 0.76 | KDM4E (0.71) | KDM4EHSP90AA1HSP90AB1EGFRNPC1 | |
| SCHEMBL15140307 | 0.75 | KDM4E (0.71) | KDM4EHSP90AA1HSP90AB1EGFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119463012-A | PH responsive hydrogel and preparation method and application thereof | 中山大学 | 2025-02-18 | — | — | CN | disclosed |