Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | JAK3 | P52333 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.42 |
| ▸ | MAP3K6 | O95382 | 1/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13134249 | 0.88 | KDM4E (0.64) | EGFRKDM4EHSP90AA1HSP90AB1JAK3 | |
| SCHEMBL31489320 | 0.88 | KDM4E (0.64) | EGFRKDM4EHSP90AA1HSP90AB1JAK3 | |
| SCHEMBL29186499 | 0.79 | KDM4E (0.68) | EGFRKDM4EHSP90AA1HSP90AB1NPC1 | |
| SCHEMBL13134396 | 0.78 | RAB9A (0.60) | KDM4ENPC1RAB9AALDH1A1POLB | |
| SCHEMBL13134398 | 0.76 | EGFR (0.41) | EGFRJAK3NPC1RAB9APOLB | |
| SCHEMBL11525532 | 0.74 | KDM4E (0.54) | KDM4EHSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL29432901 | 0.74 | KDM4E (0.69) | KDM4EHSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL13134395 | 0.74 | KDM4E (0.51) | KDM4ENPC1RAB9AALDH1A1POLB | |
| SCHEMBL8515227 | 0.73 | KDM4E (0.70) | KDM4EHSP90AA1HSP90AB1NPC1RAB9A | |
| SCHEMBL13134353 | 0.73 | MEN1 (0.48) | EGFRKDM4EHSP90AA1HSP90AB1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247938-A1 | MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100247938-A1 | MATERIAL FOR THREE-DIMENSIONAL MODELING, PROCESS FOR PRODUCING THREE-DIMENSIONAL MODEL, AND THREE-DIMENSIONAL MODEL | FUJIFILM CORPORATION (JP) | 2010-09-30 | — | — | US | disclosed |