SCHEMBL31489328

SCHEMBL31489328

CC(F)(F)C(c1ccc(F)cc1)n1cc(B2OC(C)(C)C(C)(C)O2)cn1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.44
LPL P06858 1/20 0.43
LIPG Q9Y5X9 1/20 0.43
ESR2 Q92731 1/20 0.31
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
F11 P03951 1/20 0.31
CXCR2 P25025 1/20 0.30
IDO1 P14902 1/20 0.30
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489214 1.00 FFAR1 (0.44) FFAR1LPLLIPGESR2F2
SCHEMBL31489648 0.92 LPL (0.43) FFAR1LPLLIPGESR2F2
SCHEMBL31489362 0.92 LPL (0.43) FFAR1LPLLIPGESR2F2
SCHEMBL15653015 0.83 LPL (0.47) FFAR1LPLLIPGESR2CXCR2
SCHEMBL31489511 0.83 LPL (0.47) FFAR1LPLLIPGESR2CXCR2
SCHEMBL31489793 0.81 FFAR1 (0.43) FFAR1LPLLIPGESR2CXCR2
SCHEMBL22558697 0.81 LPL (0.44) FFAR1LPLLIPGESR2CXCR2
SCHEMBL31489712 0.80 LPL (0.43) FFAR1LPLLIPGESR2CXCR2
SCHEMBL22585809 0.80 LPL (0.43) FFAR1LPLLIPGESR2CXCR2
SCHEMBL31489271 0.80 LPL (0.43) FFAR1LPLLIPGESR2CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed