SCHEMBL31489381

SCHEMBL31489381

Nc1nc2cc(-c3nc(-c4cnn(C(c5ccc(F)cc5)C5CC5)c4)ccc3F)ccn2n1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PIK3CG P48736 9/20 0.35
NTRK1 P04629 1/20 0.33
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
PIK3CD O00329 7/20 0.32
RIPK1 Q13546 1/20 0.32
PIK3CA P42336 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31489483 0.97 NTRK1 (0.34) PIK3CGNTRK1BRD4CREBBPPIK3CD
SCHEMBL31489333 0.92 PIK3CG (0.33) PIK3CGNTRK1PIK3CDRIPK1PIK3CA
SCHEMBL31489825 0.89 PIK3CG (0.31) PIK3CGNTRK1PIK3CDRIPK1PIK3CA
SCHEMBL31489781 0.87 PIK3CG (0.38) PIK3CGNTRK1BRD4CREBBPPIK3CD
SCHEMBL31489660 0.86 BRD4 (0.35) NTRK1BRD4CREBBP
SCHEMBL31489703 0.86 PIK3CG (0.36) PIK3CGNTRK1CREBBPPIK3CDRIPK1
SCHEMBL31489539 0.84 PIK3CG (0.34) PIK3CGPIK3CDRIPK1PIK3CA
SCHEMBL31489386 0.84 PIK3CG (0.35) PIK3CGNTRK1PIK3CDRIPK1PIK3CA
SCHEMBL31489516 0.84 PIK3CG (0.35) PIK3CGNTRK1PIK3CDRIPK1PIK3CA
SCHEMBL31489200 0.84 PIK3CG (0.33) PIK3CGNTRK1PIK3CDRIPK1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed