Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 14/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PAK4 | O96013 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.38 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489831 | 0.92 | PIK3CG (0.39) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489720 | 0.92 | PIK3CG (0.39) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489823 | 0.89 | PIK3CG (0.49) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489383 | 0.88 | PIK3CG (0.38) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489277 | 0.88 | PIK3CG (0.38) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489875 | 0.88 | PIK3CG (0.38) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489797 | 0.87 | PIK3CG (0.40) | PIK3CGPIK3CDPIK3CAPAK4JAK1 | |
| SCHEMBL31489796 | 0.87 | ROCK2 (0.31) | ROCK2 | |
| SCHEMBL31489635 | 0.87 | ROCK2 (0.31) | ROCK2 | |
| SCHEMBL31489725 | 0.86 | PIK3CG (0.40) | PIK3CGPIK3CDPIK3CAPAK4JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |