Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.61 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910272 | 0.84 | L3MBTL1 (0.65) | L3MBTL1KCNH2DYRK1BCREBBPPIK3CD | |
| SCHEMBL1128744 | 0.83 | L3MBTL1 (0.78) | L3MBTL1KCNH2DYRK1BCREBBPPIK3CD | |
| SCHEMBL983078 | 0.82 | L3MBTL1 (0.71) | L3MBTL1KCNH2DYRK1BCREBBPPIK3CD | |
| SCHEMBL15344194 | 0.82 | L3MBTL1 (0.71) | L3MBTL1KCNH2CREBBPPIK3CDPIK3CA | |
| SCHEMBL8379718 | 0.80 | KCNH2 (0.61) | L3MBTL1KCNH2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL15340955 | 0.79 | L3MBTL1 (0.66) | L3MBTL1KCNH2CREBBPPIK3CDPIK3CA | |
| SCHEMBL671242 | 0.77 | TSHR (0.63) | L3MBTL1DYRK1BCREBBPADORA2AADORA1 | |
| SCHEMBL3713180 | 0.77 | L3MBTL1 (0.62) | L3MBTL1CREBBPPIK3CDPIK3CAPIK3CB | |
| SCHEMBL8377006 | 0.77 | KCNH2 (0.54) | L3MBTL1KCNH2MEN1KMT2AGABRG2 | |
| SCHEMBL20515406 | 0.76 | L3MBTL1 (0.61) | L3MBTL1KCNH2CREBBPPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |