Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 9/20 | 0.37 |
| ▸ | JAK1 | P23458 | 9/20 | 0.37 |
| ▸ | TYK2 | P29597 | 9/20 | 0.37 |
| ▸ | JAK3 | P52333 | 9/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 3/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.32 |
| ▸ | CDK9 | P50750 | 3/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489819 | 1.00 | CYP17A1 (0.40) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489183 | 0.86 | JAK2 (0.39) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489249 | 0.86 | JAK2 (0.39) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489266 | 0.86 | CYP17A1 (0.40) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489470 | 0.84 | CREBBP (0.40) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489380 | 0.84 | CREBBP (0.40) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489590 | 0.74 | CYP17A1 (0.38) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489746 | 0.74 | CYP17A1 (0.38) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL22585811 | 0.72 | CYP17A1 (0.43) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489634 | 0.72 | CYP17A1 (0.43) | CYP17A1JAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |