Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 11/20 | 0.37 |
| ▸ | JAK1 | P23458 | 10/20 | 0.37 |
| ▸ | TYK2 | P29597 | 10/20 | 0.37 |
| ▸ | JAK3 | P52333 | 10/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489438 | 0.86 | CYP17A1 (0.40) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489819 | 0.86 | CYP17A1 (0.40) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489665 | 0.81 | CYP11B2 (0.38) | CYP11B2CYP11B1 | |
| SCHEMBL31489816 | 0.81 | CYP11B2 (0.40) | JAK2JAK1TYK2JAK3CYP11B2 | |
| SCHEMBL31489553 | 0.81 | CYP11B2 (0.40) | JAK2JAK1TYK2JAK3CYP11B2 | |
| SCHEMBL31489183 | 0.77 | JAK2 (0.39) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489249 | 0.77 | JAK2 (0.39) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL22585811 | 0.72 | CYP17A1 (0.43) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL31489634 | 0.72 | CYP17A1 (0.43) | CYP17A1JAK2JAK1TYK2JAK3 | |
| SCHEMBL1464223 | 0.70 | CYP11B2 (0.57) | CYP11B2CYP11B1DRD2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072395-A1 | TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-03 | — | — | WO | disclosed |